State and local officials nationwide are imposing new coronavirus restrictions and pleading with the public in an increasingly desperate attempt to stop the explosive spread of the disease as many Americans resist calls to limit gatherings and travel heading into the holidays.

Nevada Gov. Steve Sisolak tightened restrictions on casinos, restaurants and private gatherings beginning Tuesday. Most California counties are under a curfew, and Los Angeles County officials will prohibit in-person dining for at least three weeks. Nebraska Gov. Pete Ricketts warned Monday that he could impose tighter social-distancing restrictions before Thanksgiving if hospitalizations continue to rise.

Sisolak, who has avoided tightening mandates throughout the fall because of the potential damage to Nevada’s tourism-based economy, said the trends led to an “inescapable conclusion.”

“We are on a rapid trajectory that threatens to overwhelm our health care system, our front-line health workers and your access to care. So it’s time to